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Seneca Vacation Rentals

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Our Favorite Vacation Rentals in Seneca

  • Lake Keowee Home w/ Dock - 12 Mi to Clemson Campus
    Lake Keowee Home w/ Dock - 12 Mi to Clemson Campus
    Excellent3br Home/Apartment
    HolidayLettingsFrom $426
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  • Keowee Key Golf Course/Lake Condo in Salem SC
    Keowee Key Golf Course/Lake Condo in Salem SC
    Good2br Home/Apartment
    HolidayLettingsFrom $260
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  • Experience Clemson in our charming house
    Experience Clemson in our charming house
     4br Home/Apartment
    HolidayLettingsFrom $1271
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  • Rustic style 1 bedroom Loft getaway near Clemson
    Rustic style 1 bedroom Loft getaway near Clemson
     1br Home/Apartment
    HolidayLettingsFrom $183
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  • Lakeside Getaway in Keowee Key
    Lakeside Getaway in Keowee Key
     2br Home/Apartment
    HolidayLettingsFrom $233
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  • 3 bed/2 bath Home close to Clemson
    3 bed/2 bath Home close to Clemson
    Excellent3br Home/Apartment
    AirbnbFrom $358
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  • 6 miles from Clemson, Death Valley
    6 miles from Clemson, Death Valley
    Excellent4br Home/Apartment
    AirbnbFrom $1590
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  • Clemson Game-- No Min Stay! $300.00 a night
    Clemson Game-- No Min Stay! $300.00 a night
     1br Home/Apartment
    AirbnbFrom $336
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See all 178 deals in Seneca

Seneca Vacation Rentals with a Pool

  • The Clemson Cottage
    The Clemson Cottage
    Excellent3br Home/Apartment
    AirbnbFrom $148
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  • Vacation Home with Resort Amenities on 53 acres!
    Vacation Home with Resort Amenities on 53 acres!
    Excellent3br Home/Apartment
    AirbnbFrom $550
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  • Tiger Town Getaway!
    Tiger Town Getaway!
    Excellent2br Home/Apartment
    AirbnbFrom $252
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  • Clemson Apartment
    Clemson Apartment
    Good3br Home/Apartment
    AirbnbFrom $294
    View Deal
See all deals in Seneca with a pool

Seneca Vacation Rentals with Wi-Fi

  • Great deal just 5 miles from Clemson!
    Great deal just 5 miles from Clemson!
    Excellent2br Home/Apartment
    AirbnbFrom $112
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  • Private guest suite near Clemson University
    Private guest suite near Clemson University
    Excellent1br Home/Apartment
    AirbnbFrom $84
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  • Private lake setting close to Clemson University
    Private lake setting close to Clemson University
    Excellent3br Home/Apartment
    AirbnbFrom $160
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  • Lake Keowee Lake Front /Dock - Amazing Sunset
    Lake Keowee Lake Front /Dock - Amazing Sunset
    Excellent5br Home/Apartment
    AirbnbFrom $704
    View Deal
See all deals in Seneca with WiFis

Seneca Pet-Friendly Vacation Rentals

  • Rest, Relax, Revive
    Rest, Relax, Revive
    Excellent3br Home/Apartment
    AirbnbFrom $336
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  • 10 minutes from Clemson football!
    10 minutes from Clemson football!
     3br Home/Apartment
    AirbnbFrom $371
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  • Cozy Lake House 5 Miles from Clemson!
    Cozy Lake House 5 Miles from Clemson!
    Excellent3br Home/Apartment
    AirbnbFrom $206
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  • Houseboat Clemson SC - Clemson Football
    Houseboat Clemson SC - Clemson Football
    Excellent2br Boat
    AirbnbFrom $224
    View Deal
See all deals in Seneca that allow pets

Seneca South Carolina Travel Guide

Perched cozily at the foot of the Blue Ridge Mountains, Seneca is a pretty little town and forms an excellent base for hiking in the region.

Things to Do in Seneca South Carolina

Many of those who pass through here do so with the intention of embarking on hiking adventures. As such, trekking through the foothills of the Blue Ridge Mountains and enjoying the wilderness ranks high in terms of the best things to do in Seneca. The Chestnut Ridge Trail, and the Apple Orchard Falls Trailhead are among the best in the area.

Best Time to Visit Seneca South Carolina

The spring and fall months are the best time to visit. At this point, it's not too hot for hiking but temperatures are still warm and pleasant in the high seventies.

Price and Availability in Seneca

Most expensive
Most availability
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The most expensive month to stay in a vacation rental in Seneca is in December, while the cheapest month is in May. The most popular time to book a vacation rental in Seneca is in the high season in September. Seneca has its low season in December, when less people are visiting and the vacation home occupancy rate drops.
The cheapest day to stay at a vacation rental in Seneca tends to be Thursday, while the most expensive day tends to be Saturday. Vacation homes in Seneca tend to be busiest on Fridays, while it tends to be much quieter on Tuesdays.

The Weather in Seneca

93º 65º
3.92
92º 61º
4.92
92º 67º
3.06
90º 38º
3.04
73º 26º
7.7
69º 25º
9.72
69º 13º
3.72
78º 27º
5.76
74º 27º
3.65
83º 34º
4.65
89º 47º
9.43
94º 62º
2.61
Jul
Aug
Sep
Oct
Nov
Dec
Jan
Feb
Mar
Apr
May
Jun
Rainy days
This climate histogram shows you the weather patterns in Seneca. The hottest month in Seneca is July, when temperatures peak at 94 ˚F. The coolest month is January, when temperatures drop to 13 ˚F. The wettest month in Seneca is December with 9.72 inches of rain, while the driest month is June with 2.61 inches of rain.

What Expert Travelers Think

Destinations near Seneca